depression
Articles tagged with “depression”

What PHQ-9 Score Change Counts as Real Ketamine Improvement
A 5-point PHQ-9 drop is the usual threshold for meaningful change, and 50% is response. See how these apply to low-dose ketamine tracking in 2026.
Ketamine Dissociation and Antidepressant Response Explained
Learn what evidence says about ketamine dissociation and antidepressant response, including what clinicians monitor. Explore protocols.
Ketamine Remission Criteria for Depression Explained
Ketamine remission criteria for depression rely on standardized scales like MADRS and HAM-D. See the score thresholds, evidence quality, and what remission means in practice.
Low-Dose Ketamine Eligibility: Who Qualifies for Treatment
Learn the diagnosis, screening, and contraindication factors that determine low-dose ketamine eligibility, and see what to ask your clinician.
Low-Dose Ketamine for Late-Life Depression: Medications
Learn how clinicians assess low-dose ketamine for late-life depression with multiple medications, risks, monitoring, and questions to ask.
Ketamine Therapy for Older Adults: Safety Considerations
What older adults and families should know about ketamine therapy safety, blood pressure monitoring, drug interactions, and clinical evidence.
What a Year of Experimental Depression Treatment Reveals
A Guardian journalist spent a year testing ketamine, TMS, and gut therapy for depression. Here's what their experience reveals about low-dose ketamine.
Microdosing Ketamine Protocols: Sub-Therapeutic Dose Approaches
What does ketamine microdosing involve? Review of dose ranges, clinical applications, safety considerations, and how it differs from standard low-dose care.
Ketamine and the Gut-Brain Axis: How the Microbiome Influences Treatment Response
An in-depth look at the emerging research connecting ketamine therapy to the gut-brain axis, including how gut microbiome composition may predict and modulate ketamine's antidepressant and analgesic effects.
Ketamine for Depression: A Comprehensive Evidence-Based Guide
An in-depth clinical guide examining the evidence for low-dose ketamine in the treatment of major depressive disorder and treatment-resistant depression. Covers mechanisms of action, clinical trial data, response predictors, duration of effect, maintenance strategies, and cost-benefit analysis.
What Is the Response Rate for Ketamine Therapy?
Approximately 50 to 70 percent of patients with treatment-resistant depression respond to a course of low-dose ketamine infusions.
Does Ketamine Affect Sleep? Low-Dose Ketamine and Sleep Architecture
Does ketamine affect sleep? Review of how low-dose ketamine influences sleep quality, insomnia, and sleep architecture in depression and chronic pain patients.
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