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depression

Articles tagged with “depression”

12 articles
What PHQ-9 Score Change Counts as Real Ketamine Improvement article visual for Low Dose Ketamine

What PHQ-9 Score Change Counts as Real Ketamine Improvement

A 5-point PHQ-9 drop is the usual threshold for meaningful change, and 50% is response. See how these apply to low-dose ketamine tracking in 2026.

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clinical

Ketamine Dissociation and Antidepressant Response Explained

Learn what evidence says about ketamine dissociation and antidepressant response, including what clinicians monitor. Explore protocols.

clinical

Ketamine Remission Criteria for Depression Explained

Ketamine remission criteria for depression rely on standardized scales like MADRS and HAM-D. See the score thresholds, evidence quality, and what remission means in practice.

clinical

Low-Dose Ketamine Eligibility: Who Qualifies for Treatment

Learn the diagnosis, screening, and contraindication factors that determine low-dose ketamine eligibility, and see what to ask your clinician.

clinical

Low-Dose Ketamine for Late-Life Depression: Medications

Learn how clinicians assess low-dose ketamine for late-life depression with multiple medications, risks, monitoring, and questions to ask.

clinical

Ketamine Therapy for Older Adults: Safety Considerations

What older adults and families should know about ketamine therapy safety, blood pressure monitoring, drug interactions, and clinical evidence.

news

What a Year of Experimental Depression Treatment Reveals

A Guardian journalist spent a year testing ketamine, TMS, and gut therapy for depression. Here's what their experience reveals about low-dose ketamine.

protocols

Microdosing Ketamine Protocols: Sub-Therapeutic Dose Approaches

What does ketamine microdosing involve? Review of dose ranges, clinical applications, safety considerations, and how it differs from standard low-dose care.

research

Ketamine and the Gut-Brain Axis: How the Microbiome Influences Treatment Response

An in-depth look at the emerging research connecting ketamine therapy to the gut-brain axis, including how gut microbiome composition may predict and modulate ketamine's antidepressant and analgesic effects.

conditions

Ketamine for Depression: A Comprehensive Evidence-Based Guide

An in-depth clinical guide examining the evidence for low-dose ketamine in the treatment of major depressive disorder and treatment-resistant depression. Covers mechanisms of action, clinical trial data, response predictors, duration of effect, maintenance strategies, and cost-benefit analysis.

research

What Is the Response Rate for Ketamine Therapy?

Approximately 50 to 70 percent of patients with treatment-resistant depression respond to a course of low-dose ketamine infusions.

conditions

Does Ketamine Affect Sleep? Low-Dose Ketamine and Sleep Architecture

Does ketamine affect sleep? Review of how low-dose ketamine influences sleep quality, insomnia, and sleep architecture in depression and chronic pain patients.

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