Protocols
Browse all protocols articles and resources.
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3 articlesMicrodosing Ketamine Protocols: Sub-Therapeutic Dose Approaches
A detailed exploration of ketamine microdosing protocols, including rationale, dosing ranges, clinical applications, safety considerations, and how microdosing compares to standard sub-anesthetic dosing for depression and chronic pain.
Discontinuing Ketamine Therapy: Tapering, Timing, and Monitoring
Clinical guidance on when and how to discontinue ketamine therapy, covering tapering protocols, relapse monitoring strategies, transition planning, and evidence-based criteria for treatment cessation.
What Happens During a Ketamine Infusion?
A ketamine infusion involves a 40-minute IV drip in a clinical setting, with vital sign monitoring and a 1 to 2 hour observation period afterward.
Telehealth Ketamine Therapy: Protocols and Best Practices
A comprehensive guide to telehealth-delivered ketamine therapy, covering regulatory frameworks, clinical protocols for remote prescribing and monitoring, patient selection, and quality standards for virtual ketamine treatment programs.
Integration Therapy After Ketamine Treatment
An evidence-based guide to psychological integration following ketamine treatment sessions, covering the neurobiological rationale for integration, therapeutic frameworks, timing considerations, and practical strategies for maximizing treatment durability.
Clinical Monitoring During Ketamine Administration: Assessment Protocols
Comprehensive guide to clinical monitoring and assessment protocols during ketamine administration, covering hemodynamic monitoring, dissociation scales, and safety benchmarks.
Treatment-Resistant Depression Algorithms: Where Ketamine Fits
Analysis of where ketamine fits within treatment-resistant depression algorithms, reviewing staging models, sequencing strategies, and evidence-based positioning in the TRD pathway.
Ketamine-Assisted Psychotherapy: Integrating Pharmacology and Psychotherapy
Comprehensive review of ketamine-assisted psychotherapy (KAP), examining models of integration between pharmacological neuroplasticity and psychotherapeutic modalities for enhanced outcomes.
Ketamine Combination Therapy: Augmentation Strategies with Existing Treatments
Review of ketamine combination therapy and augmentation strategies, examining interactions with antidepressants, lithium, benzodiazepines, and psychotherapy for optimized outcomes.
Ketamine Maintenance Infusion Protocols: Frequency and Duration Optimization
Evidence-based review of ketamine maintenance infusion protocols, covering optimal frequency, duration, tapering strategies, and long-term outcomes for sustained treatment response.
Sublingual and Oral Ketamine Protocols for At-Home Depression Treatment
An evidence-informed guide to sublingual ketamine troches and oral ketamine protocols used in at-home treatment models, including prescribing considerations, dosing strategies, telehealth integration, patient safety frameworks, and clinical monitoring requirements.
Spravato (Esketamine) Nasal Spray Protocol and Administration Guidelines
A detailed clinical guide to the FDA-approved intranasal esketamine (Spravato) protocol, covering REMS program requirements, dosing schedules, administration procedures, and post-dose monitoring for treatment-resistant depression and major depressive disorder with suicidal ideation.
Standard IV Ketamine Infusion Protocols for Treatment-Resistant Depression
A comprehensive overview of intravenous ketamine infusion protocols used in clinical settings for treatment-resistant depression, including dosing parameters, session structure, monitoring requirements, and evidence-based best practices.