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Ketamine Research and Policy Updates

News and research summaries focused on what changes in evidence, regulation, access, and clinical practice may mean for ketamine patients and providers.

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Current research, policy, FDA, DEA, trial, and access updates with patient-facing context and links to primary sources when available.

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Use news articles for context, then move to the evergreen guide or safety hub for durable treatment planning information.

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News4 min readQuick Read

Expert Highlights Critical Ketamine Patient Considerations

Dr. Benjamin Brody discusses essential patient considerations for ketamine therapy at major psychiatric conference, covering safety protocols and clinical best practices.

News3 min readQuick Read

Stanford Study: Drug Combo Extends Ketamine Anti-Suicide Effects

Stanford researchers report first drug combination to extend ketamine's rapid anti-suicide effects, potentially changing treatment protocols.

Boston Ketamine Clinics: A Window Into Real-World Use article visual for Low Dose Ketamine
News5 min readStandard

Boston Ketamine Clinics: A Window Into Real-World Use

CBS News spotlights Boston ketamine clinics treating mental health conditions. What real-world patient outcomes reveal about low-dose ketamine therapy.

What a Year of Experimental Depression Treatment Reveals article visual for Low Dose Ketamine
News6 min readStandard

What a Year of Experimental Depression Treatment Reveals

A Guardian journalist spent a year testing ketamine, TMS, and gut therapy for depression. Here's what their experience reveals about low-dose ketamine.

News6 min readStandard

FDA Clears MIND1 Trial: NRX-101 Plus Robotic TMS for Suicidality

The FDA has cleared the MIND1 trial testing NRX-101 plus robotic TMS for suicidality in treatment-resistant depression. What it means for ketamine patients.

News6 min readStandard

CBT After Esketamine Cuts Relapse Risk, Trial Finds

The CBT-ENDURE trial shows 16 weeks of CBT after esketamine significantly reduces relapse risk and suicidal ideation. What it means for ketamine patients.

News6 min readStandard

Esketamine Safety Protocols: What Clinicians Now Emphasize

A new clinical overview on esketamine nasal spray details REMS requirements, two-hour monitoring, and vitals tracking. Here's what it means for ketamine patients.

News6 min readStandard

When to Switch or Stay: NMDA Therapy Discontinuation Rates

New analysis reveals why patients stop NMDA receptor antagonist therapy—and what discontinuation data means for low-dose ketamine monitoring and dosing decisions.

News6 min readStandard

What Dropout Rates Reveal About NMDA Therapy Tolerability

New psychiatric guidance examines why patients stop NMDA antagonist therapy and what side effect data means for low-dose ketamine treatment decisions.

News5 min readStandard

When Ketamine Side Effects Signal Time to Adjust Dose

New clinical analysis examines why patients stop NMDA antagonist therapy—and how smarter dose management may improve remission outcomes in TRD.

News4 min readQuick Read

Faster TRD Remission Hinges on Measurement and Dose Timing

New analysis in Psychiatric Times shows that symptom tracking and rapid dose adjustment drive faster remission in TRD—here's what it means for ketamine care.

News6 min readStandard

What Side Effect Data Tells Us About Ketamine Dosing

New analysis of NMDA receptor antagonist side effects in treatment-resistant depression underscores why dose optimization and early monitoring matter.

News6 min readStandard

NMDA Antagonist Side Effects: What the Data Says

New clinical analysis examines why patients stop ketamine and esketamine treatment—and what smarter monitoring can do to keep them on track.

News6 min readStandard

NRx FDA Review: Preservative-Free Ketamine Moves Forward

NRx Pharmaceuticals reports progress on its FDA application for preservative-free ketamine. Here's what the formulation difference means for low-dose patients.

News6 min readStandard

Trump EO on Psychedelics: What It Means for Ketamine

President Trump's April 2026 executive order accelerating psychedelic research may reshape ketamine's regulatory and clinical landscape. Here's what we know.

News5 min readStandard

NRx Moves Closer to FDA-Approved Preservative-Free Ketamine

NRx Pharmaceuticals signals FDA review progress on its preservative-free ketamine application. What this means for patients and clinicians in 2026.

News6 min readStandard

Why Clinicians Are Pushing Harder on TRD Goals

New clinical thinking on treatment-resistant depression pushes toward true remission, not just symptom reduction. Here's what it means for ketamine patients.

News7 min readStandard

Ketamine Side Effects & When to Switch: New Clinical Guidance

New clinical guidance urges tracking PHQ-9 scores, monitoring side effects closely, and switching NMDA treatments sooner to reach remission faster.

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Rethinking Treatment-Resistant Depression Care in 2026

New clinical perspectives on treatment-resistant depression push for true remission over symptom reduction. Here's what it means for ketamine patients.

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Psychedelics Executive Order: What It Means for Ketamine

A new executive order targets psychedelic medicine access. Here's what the policy shift means for low-dose ketamine patients and providers in 2026.

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NMDA Antagonist Side Effects: What the Data Now Shows

Psychiatric Times reviews side effect profiles and dropout rates for NMDA antagonists like ketamine. Here's what it means for low-dose ketamine patients.

News5 min readStandard

Insurance Gaps in Ketamine Care — And One Fix

Most health insurers deny coverage for ketamine depression treatment in 2026. Here's what that means for patients and how access gaps are being bridged.

News5 min readStandard

How Clinicians Choose TRD Treatments in 2026

New clinical guidance on treatment-resistant depression highlights how patient preference, speed of response, and functional outcomes shape ketamine treatment decisions.

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Esketamine's Role in Treatment-Resistant Depression

A new clinical overview examines esketamine's place in TRD care, including patient selection, access barriers, and rapid-acting benefits for suicidal ideation.

News5 min readStandard

Glutamate Pathway Treatments Reshape TRD Care in 2026

A 2026 review in Psychiatric Times highlights how esketamine and glutamate-targeting drugs are changing treatment-resistant depression care.

News5 min readStandard

TRD Management: Why Remission Should Be the Goal

New clinical guidance on treatment-resistant depression urges full remission over symptom reduction — here's what it means for low-dose ketamine patients.

News5 min readStandard

TRD Experts Push for Remission, Not Just Response

Psychiatrists are shifting TRD goals from symptom reduction to full remission. Here's what that means for ketamine patients and their treatment plans.

News4 min readQuick Read

Beyond 'Less Bad': Rethinking Treatment-Resistant Depression

Clinicians are pushing beyond symptom reduction in treatment-resistant depression, aiming for full remission. Here's what that means for ketamine patients.