low dose research
Articles tagged with “low dose research”
Glutamate System Modulation by Low-Dose Ketamine
Glutamate system modulation by low-dose ketamine works through NMDA receptor blockade, an AMPA-driven glutamate surge, and BDNF-linked plasticity.
Ketamine and the Default Mode Network: Neuroimaging Evidence
How does ketamine affect the brain's default mode network? A review of fMRI, MEG, and PET studies on DMN connectivity, depression, and treatment response.
Ketamine, Neuroplasticity, and Brain-Derived Neurotrophic Factor
How does low-dose ketamine drive neuroplasticity? A look at BDNF release, TrkB and mTOR activation, and the synapse rebuilding behind its rapid antidepressant effect.
Meta-Analyses of Low-Dose Ketamine for Treatment-Resistant Depression
Meta-analyses of low-dose ketamine for treatment-resistant depression show large 24-hour effects and better durability for racemic ketamine than esketamine.
Rapid-Onset Antidepressant Mechanisms of Low-Dose Ketamine
Low-dose ketamine's rapid-onset antidepressant mechanisms explain why relief begins in hours, not weeks, via NMDA blockade and BDNF-driven synaptic growth.
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