Articles tagged with “metabolism”
Ketamine has a plasma half-life of approximately 2 to 3 hours, though its antidepressant effects persist far longer due to downstream neuroplastic changes.
A comprehensive overview of ketamine pharmacokinetics across all clinically relevant routes of administration. Covers bioavailability, volume of distribution, hepatic metabolism via CYP enzymes, half-life considerations, and the role of active metabolites.
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