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Clinical Ketamine Guides

Browse clinical resources with practical ketamine therapy guidance, safety context, provider questions, and next-step planning. Low Dose Ketamine keeps the information organized for research, comparison, and informed conversations with licensed clinicians.

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MADRS vs PHQ-9: How Ketamine Trials Measure Response article visual for Low Dose Ketamine
Clinical5 min readStandard

MADRS vs PHQ-9: How Ketamine Trials Measure Response

MADRS and PHQ-9 track ketamine's effect on depression differently. Compare response and remission thresholds and see what to ask your prescriber.

What PHQ-9 Score Change Counts as Real Ketamine Improvement article visual for Low Dose Ketamine
Clinical4 min readQuick Read

What PHQ-9 Score Change Counts as Real Ketamine Improvement

A 5-point PHQ-9 drop is the usual threshold for meaningful change, and 50% is response. See how these apply to low-dose ketamine tracking in 2026.

Ketamine Dissociation and Antidepressant Response Explained article visual for Low Dose Ketamine
Clinical8 min readStandard

Ketamine Dissociation and Antidepressant Response Explained

Learn what evidence says about ketamine dissociation and antidepressant response, including what clinicians monitor. Explore protocols.

Ketamine Remission Criteria for Depression Explained article visual for Low Dose Ketamine
Clinical4 min readQuick Read

Ketamine Remission Criteria for Depression Explained

Ketamine remission criteria for depression rely on standardized scales like MADRS and HAM-D. See the score thresholds, evidence quality, and what remission means in practice.

Low-Dose Ketamine Eligibility: Who Qualifies for Treatment article visual for Low Dose Ketamine
Clinical7 min readStandard

Low-Dose Ketamine Eligibility: Who Qualifies for Treatment

Learn the diagnosis, screening, and contraindication factors that determine low-dose ketamine eligibility, and see what to ask your clinician.

Low-Dose Ketamine for Late-Life Depression: Medications article visual for Low Dose Ketamine
Clinical11 min readStandard

Low-Dose Ketamine for Late-Life Depression: Medications

Learn how clinicians assess low-dose ketamine for late-life depression with multiple medications, risks, monitoring, and questions to ask.

Ketamine Therapy for Older Adults: Safety Considerations article visual for Low Dose Ketamine
Clinical14 min readStandard

Ketamine Therapy for Older Adults: Safety Considerations

What older adults and families should know about ketamine therapy safety, blood pressure monitoring, drug interactions, and clinical evidence.