Protocols Articles
Latest articles, insights, and updates from the blog.
What Happens During a Ketamine Infusion?
A ketamine infusion involves a 40-minute IV drip in a clinical setting, with vital sign monitoring and a 1 to 2 hour observation period afterward.
Treatment-Resistant Depression Algorithms: Where Ketamine Fits
Analysis of where ketamine fits within treatment-resistant depression algorithms, reviewing staging models, sequencing strategies, and evidence-based positioning in the TRD pathway.
Telehealth Ketamine Therapy: Protocols and Best Practices
A comprehensive guide to telehealth-delivered ketamine therapy, covering regulatory frameworks, clinical protocols for remote prescribing and monitoring, patient selection, and quality standards for virtual ketamine treatment programs.
Discontinuing Ketamine Therapy: Tapering, Timing, and Monitoring
Clinical guidance on when and how to discontinue ketamine therapy, covering tapering protocols, relapse monitoring strategies, transition planning, and evidence-based criteria for treatment cessation.
Sublingual and Oral Ketamine Protocols for At-Home Depression Treatment
An evidence-informed guide to sublingual ketamine troches and oral ketamine protocols used in at-home treatment models, including prescribing considerations, dosing strategies, telehealth integration, patient safety frameworks, and clinical monitoring requirements.
Clinical Monitoring During Ketamine Administration: Assessment Protocols
Comprehensive guide to clinical monitoring and assessment protocols during ketamine administration, covering hemodynamic monitoring, dissociation scales, and safety benchmarks.
Microdosing Ketamine Protocols: Sub-Therapeutic Dose Approaches
A detailed exploration of ketamine microdosing protocols, including rationale, dosing ranges, clinical applications, safety considerations, and how microdosing compares to standard sub-anesthetic dosing for depression and chronic pain.
Integration Therapy After Ketamine Treatment
An evidence-based guide to psychological integration following ketamine treatment sessions, covering the neurobiological rationale for integration, therapeutic frameworks, timing considerations, and practical strategies for maximizing treatment durability.
Ketamine Maintenance Infusion Protocols: Frequency and Duration Optimization
Evidence-based review of ketamine maintenance infusion protocols, covering optimal frequency, duration, tapering strategies, and long-term outcomes for sustained treatment response.
Ketamine-Assisted Psychotherapy: Integrating Pharmacology and Psychotherapy
Comprehensive review of ketamine-assisted psychotherapy (KAP), examining models of integration between pharmacological neuroplasticity and psychotherapeutic modalities for enhanced outcomes.
Standard IV Ketamine Infusion Protocols for Treatment-Resistant Depression
A comprehensive overview of intravenous ketamine infusion protocols used in clinical settings for treatment-resistant depression, including dosing parameters, session structure, monitoring requirements, and evidence-based best practices.
Spravato (Esketamine) Nasal Spray Protocol and Administration Guidelines
A detailed clinical guide to the FDA-approved intranasal esketamine (Spravato) protocol, covering REMS program requirements, dosing schedules, administration procedures, and post-dose monitoring for treatment-resistant depression and major depressive disorder with suicidal ideation.
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