Safety Articles
Latest articles, insights, and updates from the blog.
Ketamine in Pregnancy and Lactation: Safety Considerations and Data Gaps
Comprehensive review of ketamine safety in pregnancy and lactation, examining preclinical developmental toxicity, limited human data, breastfeeding transfer, and risk-benefit framework.
Ketamine Tolerance and Long-Term Use: What Clinicians Need to Know
Clinical review of tolerance development during long-term ketamine therapy, including mechanisms, detection strategies, and evidence-based management approaches.
Managing Nausea and Vomiting During Ketamine Therapy
Clinical guide to preventing and treating ketamine-induced nausea and vomiting, covering antiemetic protocols, risk factors, and non-pharmacological strategies.
Long-Term Safety Considerations for Ketamine Therapy
An evidence-based review of safety concerns associated with repeated or prolonged low-dose ketamine use, including urological toxicity, neurocognitive effects, hepatic complications, and the potential for psychological and physiological dependence.
How Long Do Ketamine Side Effects Last?
Most ketamine side effects resolve within 1 to 2 hours after an infusion ends, with subtle residual effects fading within 4 to 6 hours.
Ketamine and SSRIs: Drug Interaction Deep Dive
A clinician-focused analysis of pharmacological interactions between ketamine and selective serotonin reuptake inhibitors, covering serotonin syndrome risk, clinical evidence on concurrent use, and dosing adjustment considerations.
Ketamine and Bladder Health: Urological Safety at Therapeutic Doses
A clinical review of ketamine-associated urological toxicity, examining the evidence at recreational versus therapeutic dose levels, pathophysiological mechanisms, risk factors, monitoring recommendations, and protective strategies for patients receiving low-dose ketamine treatment.
Ketamine and Liver Function Tests: Monitoring LFTs During Therapy
A clinical guide to liver function test monitoring during low-dose ketamine therapy, including baseline assessment, frequency of testing, interpreting abnormal results, and managing hepatotoxicity risk.
Ketamine and Blood Pressure: What Patients Should Know
A patient-oriented clinical guide to understanding ketamine's effects on blood pressure, including why blood pressure rises during treatment, what levels are expected, who is at increased risk, and how clinicians manage cardiovascular responses.
Ketamine and Benzodiazepines: Clinical Interaction Guide
An evidence-based analysis of the interaction between ketamine and benzodiazepines, examining efficacy attenuation, timing considerations, clinical evidence, and management strategies for prescribers.
Is Ketamine Therapy Addictive?
When administered in a supervised clinical setting at low doses, ketamine therapy carries a low risk of addiction, though the drug does have abuse potential.
Low-Dose Ketamine and Alcohol: Patient Safety Guide
A safety-focused guide on the risks and clinical considerations of alcohol use during ketamine therapy, covering pharmacological interactions, metabolism, timing guidelines, and patient counseling strategies.
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