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TRD Management: Why Remission Should Be the Goal
New clinical guidance on treatment-resistant depression urges full remission over symptom reduction — here's what it means for low-dose ketamine patients.
TRD Experts Push for Remission, Not Just Response
Psychiatrists are shifting TRD goals from symptom reduction to full remission. Here's what that means for ketamine patients and their treatment plans.
Beyond 'Less Bad': Rethinking Treatment-Resistant Depression
Clinicians are pushing beyond symptom reduction in treatment-resistant depression, aiming for full remission. Here's what that means for ketamine patients.
Ketamine and Immune Function: Immunomodulatory Effects of Low-Dose Ketamine
A research-focused review of ketamine's effects on the immune system, including its impact on innate and adaptive immunity, inflammatory cytokines, immune cell function, and implications for patients with autoimmune conditions and chronic inflammation.
Ketamine and Liver Function Tests: Monitoring LFTs During Therapy
A clinical guide to liver function test monitoring during low-dose ketamine therapy, including baseline assessment, frequency of testing, interpreting abnormal results, and managing hepatotoxicity risk.
Low-Dose Ketamine for Phantom Limb Pain: Mechanisms, Evidence, and Treatment Approaches
Can low-dose ketamine help phantom limb pain? Review of NMDA-mediated central sensitization, infusion and oral protocols, and outcomes in amputee patients.
Low-Dose Ketamine for Complex Regional Pain Syndrome (CRPS)
How is low-dose ketamine used for complex regional pain syndrome? Review of infusion protocols, oral maintenance, and multimodal care strategies.
Low-Dose Ketamine for Eating Disorders: Anorexia, Bulimia, and Binge Eating
Exploring the emerging evidence for low-dose ketamine therapy in treating anorexia nervosa, bulimia nervosa, and binge eating disorder, including mechanisms, clinical findings, and safety considerations.
Ketamine Therapy in Rural Communities: Overcoming Access Barriers
How are rural patients accessing low-dose ketamine therapy? Review of telehealth models, sublingual at-home protocols, and barriers to in-clinic care.
Microdosing Ketamine Protocols: Sub-Therapeutic Dose Approaches
What does ketamine microdosing involve? Review of dose ranges, clinical applications, safety considerations, and how it differs from standard low-dose care.
Ketamine and the Gut-Brain Axis: How the Microbiome Influences Treatment Response
An in-depth look at the emerging research connecting ketamine therapy to the gut-brain axis, including how gut microbiome composition may predict and modulate ketamine's antidepressant and analgesic effects.
Tracking Treatment Response to Ketamine: PHQ-9, MADRS, and Clinical Scales
A clinician's guide to systematic outcome measurement in ketamine therapy, covering validated rating scales, assessment frequency, response and remission thresholds, and data-driven decision-making for dosing adjustments.