Blog
Latest articles, insights, and updates from the blog.
The Complete Guide to Low-Dose Ketamine Therapy
A comprehensive, evidence-based guide covering what low-dose ketamine is, how it works, all routes of administration, what patients can expect during treatment, efficacy data across conditions, safety considerations, and how to find qualified providers.
Drug Interactions and Contraindications
Essential information about medications that may interact with ketamine therapy, who should avoid treatment, and how to safely manage concurrent medications.
Research and Clinical Evidence
Questions and answers about the scientific evidence supporting ketamine therapy, FDA approval status, landmark clinical trials, and the direction of ongoing research.
The Ketamine Treatment Process
Detailed answers about how ketamine therapy sessions work, including preparation, what happens during treatment, session duration, frequency, and aftercare.
IV vs Oral Ketamine: Routes of Administration Compared
Clinical comparison of intravenous and oral ketamine for depression and pain, examining bioavailability, efficacy evidence, convenience, cost, monitoring requirements, and appropriate clinical settings.
Getting Started with Ketamine Therapy
Answers to common questions about beginning low-dose ketamine treatment, including candidacy, finding providers, what to expect, and costs.
IV Racemic Ketamine vs Esketamine (Spravato): A Clinical Comparison
Evidence-based comparison of IV racemic ketamine and intranasal esketamine (Spravato) for treatment-resistant depression, examining mechanism differences, efficacy data, FDA status, cost, access, and side effects.
Sublingual vs Oral (Swallowed) Ketamine: Absorption and Efficacy Differences
Detailed comparison of sublingual and oral (swallowed) ketamine administration routes, covering bioavailability differences, onset of action, first-pass metabolism, dosing strategies, taste considerations, and clinical outcomes.
How Fast Does Ketamine Work for Depression?
Low-dose ketamine can produce antidepressant effects within hours, with most patients noticing improvement in 1 to 4 hours after an IV infusion.
How Long Do Ketamine Side Effects Last?
Most ketamine side effects resolve within 1 to 2 hours after an infusion ends, with subtle residual effects fading within 4 to 6 hours.
Does Insurance Cover Ketamine Therapy?
Most insurance plans do not cover IV ketamine infusions for depression, though FDA-approved intranasal esketamine (Spravato) has broader insurance coverage.
Is Ketamine Therapy Addictive?
When administered in a supervised clinical setting at low doses, ketamine therapy carries a low risk of addiction, though the drug does have abuse potential.
Contact Low Dose Ketamine
Send corrections, provider questions, or advertising inquiries.