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Latest articles, insights, and updates from the blog.

120 articles
Protocols4 min read

Clinical Monitoring During Ketamine Administration: Assessment Protocols

Comprehensive guide to clinical monitoring and assessment protocols during ketamine administration, covering hemodynamic monitoring, dissociation scales, and safety benchmarks.

Protocols4 min read

Microdosing Ketamine Protocols: Sub-Therapeutic Dose Approaches

A detailed exploration of ketamine microdosing protocols, including rationale, dosing ranges, clinical applications, safety considerations, and how microdosing compares to standard sub-anesthetic dosing for depression and chronic pain.

Protocols4 min read

Integration Therapy After Ketamine Treatment

An evidence-based guide to psychological integration following ketamine treatment sessions, covering the neurobiological rationale for integration, therapeutic frameworks, timing considerations, and practical strategies for maximizing treatment durability.

Protocols4 min read

Ketamine Maintenance Infusion Protocols: Frequency and Duration Optimization

Evidence-based review of ketamine maintenance infusion protocols, covering optimal frequency, duration, tapering strategies, and long-term outcomes for sustained treatment response.

Protocols4 min read

Ketamine-Assisted Psychotherapy: Integrating Pharmacology and Psychotherapy

Comprehensive review of ketamine-assisted psychotherapy (KAP), examining models of integration between pharmacological neuroplasticity and psychotherapeutic modalities for enhanced outcomes.

Protocols4 min read

Standard IV Ketamine Infusion Protocols for Treatment-Resistant Depression

A comprehensive overview of intravenous ketamine infusion protocols used in clinical settings for treatment-resistant depression, including dosing parameters, session structure, monitoring requirements, and evidence-based best practices.

Protocols4 min read

Spravato (Esketamine) Nasal Spray Protocol and Administration Guidelines

A detailed clinical guide to the FDA-approved intranasal esketamine (Spravato) protocol, covering REMS program requirements, dosing schedules, administration procedures, and post-dose monitoring for treatment-resistant depression and major depressive disorder with suicidal ideation.

Guides4 min read

Ketamine for Depression: A Comprehensive Evidence-Based Guide

An in-depth clinical guide examining the evidence for low-dose ketamine in the treatment of major depressive disorder and treatment-resistant depression. Covers mechanisms of action, clinical trial data, response predictors, duration of effect, maintenance strategies, and cost-benefit analysis.

Protocols4 min read

Ketamine Combination Therapy: Augmentation Strategies with Existing Treatments

Review of ketamine combination therapy and augmentation strategies, examining interactions with antidepressants, lithium, benzodiazepines, and psychotherapy for optimized outcomes.

Guides4 min read

Ketamine Dosing and Administration: A Complete Clinical Guide

A comprehensive clinical reference for ketamine dosing across all routes of administration. Covers pharmacokinetics, weight-based dosing, dose-response relationships, titration strategies, route-specific protocols, special population considerations, and monitoring requirements.

Guides4 min read

The Complete Guide to Low-Dose Ketamine Therapy

A comprehensive, evidence-based guide covering what low-dose ketamine is, how it works, all routes of administration, what patients can expect during treatment, efficacy data across conditions, safety considerations, and how to find qualified providers.

Faq4 min read

The Ketamine Treatment Process

Detailed answers about how ketamine therapy sessions work, including preparation, what happens during treatment, session duration, frequency, and aftercare.

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