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Latest articles, insights, and updates from the blog.
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Low-Dose Ketamine and Alcohol: Patient Safety Guide
A safety-focused guide on the risks and clinical considerations of alcohol use during ketamine therapy, covering pharmacological interactions, metabolism, timing guidelines, and patient counseling strategies.
Discontinuing Ketamine Therapy: Tapering, Timing, and Monitoring
Clinical guidance on when and how to discontinue ketamine therapy, covering tapering protocols, relapse monitoring strategies, transition planning, and evidence-based criteria for treatment cessation.
How to Start a Ketamine Therapy Practice: A Clinician's Guide
A comprehensive guide for clinicians on launching a ketamine therapy practice, covering DEA licensing, state regulations, clinical protocols, compounding pharmacy partnerships, liability considerations, and insurance frameworks.
Ketamine and SSRIs: Drug Interaction Deep Dive
Can patients take SSRIs during low-dose ketamine therapy? Review of pharmacodynamic overlap, serotonin syndrome signals, and co-prescribing patterns.
Low-Dose Ketamine and Cannabis: What Patients Should Know
An evidence-based overview of the interaction between low-dose ketamine therapy and cannabis use, covering pharmacological considerations, clinical evidence, timing guidance, and provider perspectives.
Ketamine and Benzodiazepines: Clinical Interaction Guide
How do benzodiazepines affect low-dose ketamine response? Review of GABAergic blunting, pre-session timing, taper considerations, and clinical findings.
Low-Dose Ketamine Case Studies: Clinical Outcomes and Lessons
What do published low-dose ketamine case studies show? Review of clinical outcomes, dosing patterns, and lessons across depression, pain, and anxiety cases.
Dosing and Administration
Common questions about ketamine dosing, routes of administration, weight-based calculations, dose adjustments, and the differences between clinic and at-home treatment.
Ketamine Dosing and Administration: A Complete Clinical Guide
Reference guide to ketamine dosage across IV, oral, sublingual troche, and intranasal routes — weight-based dosing, titration, and route-specific protocols.
IV Racemic Ketamine vs Esketamine (Spravato): A Clinical Comparison
Evidence-based comparison of IV racemic ketamine and intranasal esketamine (Spravato) for treatment-resistant depression, examining mechanism differences, efficacy data, FDA status, cost, access, and side effects.
Getting Started with Ketamine Therapy
Answers to common questions about beginning low-dose ketamine treatment, including candidacy, finding providers, what to expect, and costs.
Ketamine vs TMS (Transcranial Magnetic Stimulation): Two Approaches to Treatment-Resistant Depression
Ketamine vs TMS for treatment-resistant depression: mechanisms, success rates, protocols, side effects, FDA status, and cost compared side by side.