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Low-Dose Ketamine for Phantom Limb Pain: Mechanisms, Evidence, and Treatment Approaches
Can low-dose ketamine help phantom limb pain? Review of NMDA-mediated central sensitization, infusion and oral protocols, and outcomes in amputee patients.
Ketamine and Benzodiazepines: Clinical Interaction Guide
How benzodiazepines affect ketamine's antidepressant response: GABA vs. glutamate mechanisms, dosing strategies, taper timing, and what the clinical evidence shows.
Tracking Treatment Response to Ketamine: PHQ-9, MADRS, and Clinical Scales
Learn how PHQ-9, MADRS, QIDS-SR, and safety measures can track ketamine treatment response and support informed clinical follow-up.
Low-Dose Ketamine and Alcohol: Patient Safety Guide
Low dose ketamine and alcohol should not be combined. Learn the interaction risks, screening steps, and 24-hour abstinence guidelines for safe treatment.
Low-Dose Ketamine Case Studies: Clinical Outcomes and Lessons
Review five low-dose ketamine composite case studies, including depression, PTSD, CRPS, bipolar depression, and suicidal ideation, with research-backed clinical lessons.
How to Start a Ketamine Therapy Practice: A Clinician's Guide
A clinician guide to starting a ketamine therapy practice, covering registration, state review, protocols, monitoring, compounding, documentation, staffing, and referrals.
Low-Dose Ketamine and Cannabis: What Patients Should Know
Learn what is known about low dose ketamine and cannabis, including overlapping effects, cautious timing guidance, CBD considerations, and questions to discuss with your clinician.
Discontinuing Ketamine Therapy: Tapering, Timing, and Monitoring
Clinical guidance on when and how to discontinue ketamine therapy, covering tapering protocols, relapse monitoring strategies, transition planning, and evidence-based criteria for treatment cessation.
Ketamine and SSRIs: Drug Interaction Deep Dive
Can you take ketamine while on an SSRI? Review the serotonin syndrome risk, drug interaction evidence, and monitoring steps clinicians recommend.
The Ketamine Treatment Process
Learn what a ketamine treatment process for PTSD may involve, including assessment, preparation, monitoring, recovery, and questions to ask a clinician.
IV Racemic Ketamine vs Esketamine (Spravato): A Clinical Comparison
Evidence-based comparison of IV racemic ketamine and intranasal esketamine (Spravato) for treatment-resistant depression, examining mechanism differences, efficacy data, FDA status, cost, access, and side effects.
Safety and Side Effects
Learn about common low-dose ketamine side effects, serious safety considerations, driving restrictions, medication review, and questions to ask a clinician.