Blog
Latest articles, insights, and updates from the blog.
How to Prepare for Your First Ketamine Therapy Session
A comprehensive patient-oriented guide to preparing for an initial ketamine treatment session, covering what to expect, pre-treatment medical requirements, medication considerations, practical logistics, and strategies for optimizing treatment outcomes.
Low-Dose Ketamine for Chronic Migraine
A clinical review of subanesthetic ketamine for chronic and refractory migraine, including NMDA receptor mechanisms in migraine pathophysiology, evidence from clinical studies, infusion protocols, and safety considerations.
Biomarkers for Predicting Ketamine Treatment Response
A review of emerging biological markers that may predict which patients will respond to ketamine therapy, including inflammatory markers, neuroimaging signatures, genetic polymorphisms, and electrophysiological features.
Ketamine and Neuroinflammation: How Anti-Inflammatory Effects Support Mental Health
An evidence-based review of ketamine's anti-inflammatory mechanisms, including cytokine modulation, microglial regulation, and blood-brain barrier effects, and how these properties contribute to its antidepressant efficacy.
Integration Therapy After Ketamine Treatment
An evidence-based guide to psychological integration following ketamine treatment sessions, covering the neurobiological rationale for integration, therapeutic frameworks, timing considerations, and practical strategies for maximizing treatment durability.
Ketamine and Bladder Health: Urological Safety at Therapeutic Doses
A clinical review of ketamine-associated urological toxicity, examining the evidence at recreational versus therapeutic dose levels, pathophysiological mechanisms, risk factors, monitoring recommendations, and protective strategies for patients receiving low-dose ketamine treatment.
Ketamine and Blood Pressure: What Patients Should Know
A patient-oriented clinical guide to understanding ketamine's effects on blood pressure, including why blood pressure rises during treatment, what levels are expected, who is at increased risk, and how clinicians manage cardiovascular responses.
Ketamine Tolerance: Understanding Dose Adjustments Over Time
A clinical review of tolerance development during repeated ketamine treatment, covering pharmacological mechanisms of tolerance, clinical indicators, evidence-based dose adjustment strategies, and the distinction between therapeutic tolerance and treatment failure.
Low-Dose Ketamine for Postpartum Depression
A clinical review of low-dose ketamine as a treatment for postpartum depression, covering the neurobiological rationale, clinical evidence, safety considerations during lactation, and practical protocols for this vulnerable patient population.
Cost-Effectiveness of Ketamine Therapy: Health Economic Evidence
Health economic analysis of ketamine therapy cost-effectiveness, examining direct treatment costs, comparative value versus alternatives, QALY gains, and payer perspectives.
Ketamine in Pregnancy and Lactation: Safety Considerations and Data Gaps
Comprehensive review of ketamine safety in pregnancy and lactation, examining preclinical developmental toxicity, limited human data, breastfeeding transfer, and risk-benefit framework.
Sex Differences in Ketamine Treatment Response: Hormonal and Genetic Factors
Examining sex differences in ketamine treatment response, covering estrogen-NMDA interactions, progesterone modulation, genetic factors, and implications for personalized dosing.
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