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Latest articles, insights, and updates from the blog.

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Pharmacokinetics1 min read

How Fast Does Ketamine Work for Depression?

Low-dose ketamine can produce antidepressant effects within hours, with most patients noticing improvement in 1 to 4 hours after an IV infusion.

Pharmacokinetics1 min read

How Long Do Ketamine's Antidepressant Effects Last?

The antidepressant effects of a single ketamine infusion typically last 3 to 14 days, with repeated treatments extending the duration of benefit.

Protocols1 min read

Integration Therapy After Ketamine Treatment

What does integration therapy after a ketamine session involve? Review of neurobiological rationale, timing, therapeutic frameworks, and durability of outcomes.

Conditions1 min read

Low-Dose Ketamine for Chronic Migraine

A clinical review of subanesthetic ketamine for chronic and refractory migraine, including NMDA receptor mechanisms in migraine pathophysiology, evidence from clinical studies, infusion protocols, and safety considerations.

Research1 min read

Biomarkers for Predicting Ketamine Treatment Response

A review of emerging biological markers that may predict which patients will respond to ketamine therapy, including inflammatory markers, neuroimaging signatures, genetic polymorphisms, and electrophysiological features.

Conditions1 min read

Low-Dose Ketamine for Postpartum Depression

A clinical review of low-dose ketamine as a treatment for postpartum depression, covering the neurobiological rationale, clinical evidence, safety considerations during lactation, and practical protocols for this vulnerable patient population.

Safety1 min read

Ketamine and Blood Pressure: What Patients Should Know

A patient-oriented clinical guide to understanding ketamine's effects on blood pressure, including why blood pressure rises during treatment, what levels are expected, who is at increased risk, and how clinicians manage cardiovascular responses.

Safety1 min read

Ketamine and Bladder Health: Urological Safety at Therapeutic Doses

Does low-dose ketamine cause bladder problems? Review of urological risk at therapeutic vs recreational doses, mechanisms, and monitoring recommendations.

At Home Monitoring1 min read

Telehealth Ketamine Therapy: Protocols and Best Practices

How does telehealth ketamine therapy work? Review of remote prescribing rules, sublingual protocols, patient selection, and monitoring in virtual care models.

At Home Monitoring1 min read

How to Prepare for Your First Ketamine Therapy Session

A comprehensive patient-oriented guide to preparing for an initial ketamine treatment session, covering what to expect, pre-treatment medical requirements, medication considerations, practical logistics, and strategies for optimizing treatment outcomes.

Research1 min read

Ketamine and Neuroinflammation: How Anti-Inflammatory Effects Support Mental Health

An evidence-based review of ketamine's anti-inflammatory mechanisms, including cytokine modulation, microglial regulation, and blood-brain barrier effects, and how these properties contribute to its antidepressant efficacy.

Dosing1 min read

Ketamine Tolerance: Understanding Dose Adjustments Over Time

Do patients build tolerance to ketamine? A clinical review of tolerance mechanisms, clinical signs, and evidence on adjusting dose over repeated treatment.