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Latest articles, insights, and updates from the blog.

120 articles
Conditions4 min read

Ketamine-Assisted Therapy for PTSD and Trauma

A clinical examination of low-dose ketamine as an adjunct to psychotherapy for post-traumatic stress disorder, exploring its neurobiological rationale, emerging trial data, and integration with trauma-focused therapeutic modalities.

Conditions4 min read

Ketamine for OCD: Glutamatergic Modulation of Obsessive-Compulsive Circuits

Review of ketamine in OCD treatment, examining glutamatergic modulation of cortico-striato-thalamo-cortical circuits, clinical trial evidence, and rapid anti-obsessional effects.

Conditions4 min read

Low-Dose Ketamine for Phantom Limb Pain: Mechanisms, Evidence, and Treatment Approaches

A comprehensive review of low-dose ketamine therapy for phantom limb pain, covering the neuroscience of phantom sensations, clinical evidence for ketamine treatment, dosing protocols, and integration with multimodal pain management.

Conditions4 min read

Low-Dose Ketamine Infusions for Neuropathic Pain: Evidence and Protocols

Evidence-based review of low-dose ketamine infusions for neuropathic pain, covering NMDA receptor mechanisms, clinical trial outcomes, infusion protocols, and patient selection.

Conditions4 min read

Does Ketamine Help with PTSD?

Early research suggests low-dose ketamine can rapidly reduce PTSD symptoms, though it is not yet an established first-line treatment for the condition.

Conditions4 min read

Low-Dose Ketamine for Postpartum Depression

A clinical review of low-dose ketamine as a treatment for postpartum depression, covering the neurobiological rationale, clinical evidence, safety considerations during lactation, and practical protocols for this vulnerable patient population.

Conditions4 min read

Can Ketamine Help with Chronic Pain?

Low-dose ketamine can provide significant relief for certain chronic pain conditions by blocking NMDA receptors involved in central sensitization.

Conditions4 min read

Low-Dose Ketamine for Chronic Migraine

A clinical review of subanesthetic ketamine for chronic and refractory migraine, including NMDA receptor mechanisms in migraine pathophysiology, evidence from clinical studies, infusion protocols, and safety considerations.

Conditions4 min read

Does Ketamine Affect Sleep? Low-Dose Ketamine and Sleep Architecture

Evidence-based review of how low-dose ketamine affects sleep quality, architecture, and insomnia in patients with depression and chronic pain.

Conditions4 min read

Sub-Anesthetic Ketamine for Fibromyalgia: Analgesic Mechanisms and Outcomes

Evidence review of sub-anesthetic ketamine for fibromyalgia pain, examining central sensitization reversal, NMDA receptor mechanisms, and clinical outcomes from infusion studies.

Conditions4 min read

Low-Dose Ketamine for Eating Disorders: Anorexia, Bulimia, and Binge Eating

Exploring the emerging evidence for low-dose ketamine therapy in treating anorexia nervosa, bulimia nervosa, and binge eating disorder, including mechanisms, clinical findings, and safety considerations.

Conditions4 min read

Low-Dose Ketamine for Complex Regional Pain Syndrome (CRPS)

A comprehensive guide to using low-dose ketamine for complex regional pain syndrome, covering the pathophysiology of CRPS, evidence for ketamine treatment, infusion protocols, oral maintenance strategies, and multimodal care integration.

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