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Latest articles, insights, and updates from the blog.

139 articles
Protocols4 min read

Clinical Monitoring During Ketamine Administration: Assessment Protocols

Comprehensive guide to clinical monitoring and assessment protocols during ketamine administration, covering hemodynamic monitoring, dissociation scales, and safety benchmarks.

Safety4 min read

Abuse Potential of Therapeutic Ketamine: Risk Stratification and Monitoring

Assessment of abuse potential for therapeutic ketamine, examining risk stratification approaches, monitoring strategies, and safeguards for clinical prescribing programs.

Dosing4 min read

Pediatric Low-Dose Ketamine: Dosing Considerations and Safety

Review of pediatric low-dose ketamine dosing considerations, covering developmental pharmacokinetics, age-specific safety data, and clinical applications in children and adolescents.

Protocols4 min read

Treatment-Resistant Depression Algorithms: Where Ketamine Fits

Analysis of where ketamine fits within treatment-resistant depression algorithms, reviewing staging models, sequencing strategies, and evidence-based positioning in the TRD pathway.

Clinical4 min read

Low-Dose Ketamine in Emergency Psychiatry: Acute Management Protocols

Review of low-dose ketamine in emergency psychiatry settings, covering acute suicidal ideation management, agitation protocols, ED implementation, and rapid assessment frameworks.

Conditions4 min read

Low-Dose Ketamine Infusions for Neuropathic Pain: Evidence and Protocols

Evidence-based review of low-dose ketamine infusions for neuropathic pain, covering NMDA receptor mechanisms, clinical trial outcomes, infusion protocols, and patient selection.

Research4 min read

Glutamate System Modulation by Low-Dose Ketamine

A comprehensive analysis of how low-dose ketamine modulates the glutamate system, including NMDA receptor antagonism, AMPA receptor potentiation, and the glutamate surge hypothesis. Reviews the excitatory-inhibitory balance framework and its therapeutic implications.

Research4 min read

Ketamine Effects on Sleep Architecture: Slow-Wave Sleep and REM Changes

Examining ketamine's effects on sleep architecture including slow-wave sleep enhancement, REM sleep modulation, and implications for the sleep-depression-neuroplasticity axis.

Protocols4 min read

Ketamine-Assisted Psychotherapy: Integrating Pharmacology and Psychotherapy

Comprehensive review of ketamine-assisted psychotherapy (KAP), examining models of integration between pharmacological neuroplasticity and psychotherapeutic modalities for enhanced outcomes.

Clinical4 min read

Telehealth Ketamine Marketing Compliance: Regulatory and Ethical Guidelines

Regulatory guide for marketing at-home ketamine therapy and esketamine services, covering FDA rules, DEA requirements, and state telemedicine laws.

Conditions4 min read

Sub-Anesthetic Ketamine for Fibromyalgia: Analgesic Mechanisms and Outcomes

Evidence review of sub-anesthetic ketamine for fibromyalgia pain, examining central sensitization reversal, NMDA receptor mechanisms, and clinical outcomes from infusion studies.

Safety4 min read

Ketamine Side Effects: A Complete Clinical Guide

Comprehensive evidence-based review of ketamine side effects including dissociation, nausea, cardiovascular changes, and cognitive effects for clinicians.

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