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Latest articles, insights, and updates from the blog.

155 articles

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Research1 min read

Telehealth Ketamine Marketing Compliance: Regulatory and Ethical Guidelines

What rules govern telehealth ketamine advertising? Review of FDA, FTC, and state guidance on marketing low-dose ketamine therapy through virtual platforms.

Safety1 min read

Ketamine Side Effects: A Complete Clinical Guide

Comprehensive evidence-based review of ketamine side effects including dissociation, nausea, cardiovascular changes, and cognitive effects for clinicians.

Conditions1 min read

Sub-Anesthetic Ketamine for Fibromyalgia: Analgesic Mechanisms and Outcomes

Evidence review of sub-anesthetic ketamine for fibromyalgia pain, examining central sensitization reversal, NMDA receptor mechanisms, and clinical outcomes from infusion studies.

Safety1 min read

Ketamine Tolerance and Long-Term Use: What Clinicians Need to Know

Clinical review of tolerance development during long-term ketamine therapy, including mechanisms, detection strategies, and evidence-based management approaches.

Safety1 min read

Managing Nausea and Vomiting During Ketamine Therapy

Clinical guide to preventing and treating ketamine-induced nausea and vomiting, covering antiemetic protocols, risk factors, and non-pharmacological strategies.

Safety1 min read

Cognitive Effects of Repeated Low-Dose Ketamine: Neuropsychological Assessment

Does repeated low-dose ketamine affect cognition? Review of memory, attention, and executive function testing across short- and longer-term treatment courses.

Conditions1 min read

Does Ketamine Affect Sleep? Low-Dose Ketamine and Sleep Architecture

Does ketamine affect sleep? Review of how low-dose ketamine influences sleep quality, insomnia, and sleep architecture in depression and chronic pain patients.

At Home Monitoring1 min read

Measuring Ketamine Treatment Outcomes: Validated Assessment Tools

How is ketamine response actually measured? A review of validated depression scales, suicidality tools, functional assessments, and biomarkers used in trials.

Dosing1 min read

Esketamine vs Racemic Ketamine Dosing: Comparative Pharmacology

How do esketamine and racemic ketamine doses compare? Review of enantiomer pharmacology, potency differences, route-specific dosing, and clinical equivalencies.

Research1 min read

Anti-Inflammatory Properties of Low-Dose Ketamine: Cytokine Modulation

Review of the anti-inflammatory properties of low-dose ketamine, examining cytokine modulation, NF-kappaB signaling, microglial inhibition, and implications for depression and pain.

Research1 min read

BDNF Signaling and Ketamine's Antidepressant Action

A detailed examination of how ketamine activates brain-derived neurotrophic factor signaling, TrkB receptor pathways, and the mTOR cascade to produce rapid antidepressant effects. Covers molecular mechanisms, clinical evidence, and implications for personalized treatment.

Conditions1 min read

Ketamine-Assisted Therapy for Substance Use Disorders: Clinical Trials Review

Review of ketamine-assisted therapy for substance use disorders including alcohol, cocaine, and opioid dependence — examining clinical trials, neuroplasticity mechanisms, and outcomes.